TECHNOLOGY USED
Well-equipped laboratories for work under infectious
and non-infections conditions. The most relevant
equipments include:
• Laboratories for an identification and quantification
of proteins or lipids on the principle of mass
spectrometry and on principle of immunoassays
• Laboratories for microscopy covering also
scanning electron microscopy, confocal
microscopy, inverted epifluorescence microscopy
for live-cell imaging, laser microdissection
• Laboratories for flow cytometry allowing not only
multiparametric analyses but also cell sorting
• Laboratories for work with nucleic acids
• Laboratories for monoclonal or polyclonal
antibodies production
Modern experimental animal facility, including
infectious facility under BSL3 regime. These facilities
had an accreditation for almost all animal species
– from rodents and lagomorphs, through pigs,
cattle, and birds, up to fish. Instrumentation allows
also a detection of fluorescence, luminescence,
and radioisotopes with X-rays in live objects,
sonography or X-ray examination.
Institute has also permission for performance of
experiments with genetically modified organisms
and handling with highly hazardous
biological agents and toxins.

Additional activities
• OIE Reference laboratory for
paratuberculosis and for avian tuberculosis
• National Reference Laboratories of the State
Veterinary Administration – for Escherichia
coli and for viral diseases of fish
• Centre of accredited laboratories and
Methodical and consulting centres
• Acquisition, preservation and distribution
of zoopathogenic bacteria and animal
viruses in CAMP (Collection of Animal
Pathogenic Microorganisms)
• Activities of the Scientific Veterinary
Committee for Food Safety
RESEARCH SERVICES
Pre-clinical tests
Independent testing site for an assessment of effectiveness of developed products for active and passive immunostimulation of farm and accompany animals. Independent testing site for an assessment of effectiveness of feed additives or therapeutic protocols for farm animals.
Animal models
Using different infectious and non-infectious animal models, incl. caesarean-derived / colostrum-deprived piglets.
In vitro experiments
Using different in vitro models, including work with primary and permanent cell lines and transwell technology.
Laboratory analyses
All laboratory analyses needed to perform in vivo and in vitro experiments.

COLLABORATIVE RESEARCH ACTIVITIES
• Study of infectious diseases of farm animals,
including development of live or recombinant
vaccines.
• Development of eradication programs on
economically important diseases.
• Study of molecular epidemiology of zoonosis.
• Development of nanoparticle based vaccines,
immunotherapeutic and drug delivery systems.
• Study of occurrence and mechanisms of the bacterial
resistance to antimicrobial agents.
• Study of food chain contamination with infectious
agents.
• Study of non-infectious diseases, incl. reproductive
dysfunction and embryo transfer.
• Study of mechanisms controlling chromosome
segregation in mammalian germ cells and embryos.
• Study of the effect of contamination on animal health
and product quality.
• Study of toxicity mechanisms of food chain chemical
contaminants.
• Development of methods for determination of
xenobiotics in the environment and in biological
materials.